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Post by jonappleseed on Apr 3, 2011 3:02:32 GMT -5
I have been reading about PMMA side effects and it sounds as if the most common one is a granuloma.
In the literature on granulomas it seems as if doctors treat it as a fairly serious concern. As far as I can tell it is just a localized problem that may need to get cut out from the surface which would leave a small scar.
Is that it or is there something else I am missing that makes these things a concern?
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Post by hoddle10 on Apr 3, 2011 8:04:33 GMT -5
It depends on what you define as a granuloma. I read a chapter in a dermatalogical journal about comlications with injectable fillers. The author worked at Qmed. He basically said people are often splitting hairs between lumps and granulomas, but if it's only visible to touch and not painful, then it will usually be described as a lump. If there is inflamation, pain and can the lump can be seen, it's usually described as a granuloma. But most lumps are due to some kind of foreign body reaction, so in theory it is correct to call them granulomas, but often it's a slighlty misleading diagnosis as the word tends to have connotations and simply "lumps" would often seem a better description. Lemperle alluded to this in the email posted on here, which was one of a few messages exchanged. Basically a individual lump without inflammatory reaction, isn't the end of the world and if required should be able to be removed. However, if the whole area breaks out in lumps and inflammatory reaction it could be very hard to treat. If you don't like PMMA, then you'll call all lumps granulomas and if you are pro PMMA, then you'll only call them granulomas when they multiple and are accompained by infammatory reaction. I should have posted this in the Lemperle email thread, but I was too annoyed by the rude response by one of our members, who had no access to previous messages, but decided to question Lemperle's integrity, which is a shame given we'd invited him to view the forum.
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Post by Gengar on Apr 4, 2011 2:19:10 GMT -5
Thanks for your explanation, hoddle10, it clarified the subject of granulomas for me.
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