Post by mikehok on Mar 31, 2011 16:21:28 GMT -5
Over the last few days I have exchanged several emails with Prof Lemperle who is the inventor of pmma and is now based in San Diego. I wanted to ask him about potential complications and I also asked for his comments on the report which was posted on this site several months ago which reports various cases of complications. His reply has given me more confidence to go ahead with the procedure, and he has given me permission to post it on this board, so here it is:
" I know this report very well (and the authors Ferreira and Gemperli) - since I had to peer-review it - and was shocked as you are. One has to know that PMMA is injected in Brazil by the pounds in probably millions of patients - because it is so cheap. over there. And it was (!!) not clean, e.g. caused a lot of granulomas.
The Brazilian doctors prevented granulomas by injecting bigger amounts deep under the skin, instead of into the dermis, as we can do it with our clean ArteFill or Artecoll - or now Newplastic. Everything in medicine is development - unfortunately often on the facts of side effects.
The described necroses , therefore, were eliminated by the introduction of blunt cannulas , which are introduced and used by Dr. Casavantes , since with sharp needles, one could hit an artery and fill it unnoticed with PMMA ...until a skin necrosis became obvious - hours after the injection.
So, since I collected all complications on PMMA worldwide since 20 years, I can assure you that a skin necrosis in impossible with blunt cannulas . Granulomas still remain a risk - but so far, they occurred all after intradermal injections (because the skin is the most sensitive organ of the body) - and not after deeper injections in the fat or for example between Dartos' and Buck's fascia.
Since I have been in contact with a few patients - and saw one in N.Y. - who had lumps after PMMA injections in their buttocks, I can assure you that also the "granulomas" described in the above article have been lumps, due to uneven injection or movement and dislocation by the buttock muscles. Pathologists call every foreign body reaction a "granuloma". What they call "inflammatory reactions" to PMMA. I would call a granuloma, if it occurs 1/2 to 5 years late, on all sites at the same time.
Still, even if I don't know of any case (In China , they have injected more than 500,000 patients - and report every side effect to me) the risk of the first granuloma in a penis remains....
Hope, that helps you ?
Best , Gottfried Lemperle
" I know this report very well (and the authors Ferreira and Gemperli) - since I had to peer-review it - and was shocked as you are. One has to know that PMMA is injected in Brazil by the pounds in probably millions of patients - because it is so cheap. over there. And it was (!!) not clean, e.g. caused a lot of granulomas.
The Brazilian doctors prevented granulomas by injecting bigger amounts deep under the skin, instead of into the dermis, as we can do it with our clean ArteFill or Artecoll - or now Newplastic. Everything in medicine is development - unfortunately often on the facts of side effects.
The described necroses , therefore, were eliminated by the introduction of blunt cannulas , which are introduced and used by Dr. Casavantes , since with sharp needles, one could hit an artery and fill it unnoticed with PMMA ...until a skin necrosis became obvious - hours after the injection.
So, since I collected all complications on PMMA worldwide since 20 years, I can assure you that a skin necrosis in impossible with blunt cannulas . Granulomas still remain a risk - but so far, they occurred all after intradermal injections (because the skin is the most sensitive organ of the body) - and not after deeper injections in the fat or for example between Dartos' and Buck's fascia.
Since I have been in contact with a few patients - and saw one in N.Y. - who had lumps after PMMA injections in their buttocks, I can assure you that also the "granulomas" described in the above article have been lumps, due to uneven injection or movement and dislocation by the buttock muscles. Pathologists call every foreign body reaction a "granuloma". What they call "inflammatory reactions" to PMMA. I would call a granuloma, if it occurs 1/2 to 5 years late, on all sites at the same time.
Still, even if I don't know of any case (In China , they have injected more than 500,000 patients - and report every side effect to me) the risk of the first granuloma in a penis remains....
Hope, that helps you ?
Best , Gottfried Lemperle